CQC is definitely something in the same vein as Premise, i.e. a serious software based automation package,
I'm not sure you are doing justice to CQC by saying 'in the same vein as Premise".
Maybe "in a MUCH better vein" would be correct.
On the serious side, Premise has a long and not particularly pretty past. The concept was excellent, but the execution was somewhat lacking. It started with a premature beta release, when in reality the software should not have been qualified as even at pre-alpha level. They had to withdraw it completely, and by the time it made it back to beta, it had acquired the tag of being overhyped/oversold vaporware. It also morphed from a package for the general HA population to a integrator only package with a high pricetag. When Lantronix bought them, it seemed that the software was only marketed as a means to sell Lantronix equipment, not as the center of the HA setup. Now that Premise has been sold to Motorola, it is now with a company that has the deep pockets to really give the software some momentum, assuming that the software just doesn't disappear into the aformentioned deep pockets. Time will tell.
None of this really answers your original question though. I tried Premise a while ago, and decided that the steep learning curve did not justify the benefits (I have an IT background, so programming is not the challenge to me that it could be for many people). Talking to other integrators, they tended to echo my thoughts. Premise is very powerful, but has a very steep learning curve. Many mentioned that when you got all done with the required equipment and software, the total cost was in the same ballpark as a Crestron/Elan system, but without the long track record of success that Crestron/Elan have.[
Best bet, download copies of all the HA software packages and try them. Unlike hardware, all the good packages have some sort of 30-day try before you buy setup. It's not worth the effort for a hobbiest to do this, but if you plan on doing this as a business, you need to know the lay of the land. I myself need to put my effert where my mouth is and download CQC to give it a try.
Cripes, I'm long-winded tonight. Must be the wine.