A strike a block away sounds more like an issue coming from the power grid, Internet network connection, phone line, ham radio antenna or tv antenna/mast, or satellite dish than zones and sensors.
Wireless of course adds a layer of protection from lightning, if lightning comes through the zones and sensors but most often overlooked is that the ISP's network connection could be causing the damage (if the OPII is connected to a network).
Try adding a Planet ELA-100 lightning arrestor to the Internet network connection coming into the building or house. If the OPII, router, and switch are all connected to a UPS (they need to be), verify the UPS is grounded and remember that most UPS battery backups are designed to protect against lightning so look for any AC-powered devices connected to the OPII that are not protected by UPS like switch, router, dsl or cable modem, phone dialer module.
For those that don't know, when lightning strikes or there is a large static surge, a lightning arrestor either shunts the discharge to ground, or shunts the discharge as a short at the arrestor so as to the zones. There are plenty of lightning arrestors on the market for just about any type of device so simply follow the same principal for the OPII as anything else.
Lightning arrestors (spelled with an "o") are not cheap, which is why lightning protection is rare to find in a home, and protecting every connection is going to be difficult, plus one may need resistors to adjust zone detection, which means testing all zones again after installation too.
Look for gas tube arrestors with screw terminals like the L-com HGLN-D2 as those should be more economical but seriously I would look at the other items above first.
If you were in a commercial building, I would add that the proper way to gain protection is to hire a company specializing in building lightning protection who would surround the premise with copper grounding rods (lightning rods).
Of course a direct strike is going to hurt no matter what....