I do not automate my main house dehumidification. I use an ecobee stat for that that performs very well. I do automate my floor humidifier as well as a ventilation fan in my cold cellar using an ISY994i. I was told I wouldn't need a humidifier with my very tight seal house I built but that was a lie. If I boiled food water every night maybe, but the colds and flu living in a dry house is not worth it. My central air handler has no room and I use a large floor unit instead controlled by my ecobee stat, to ISY994i, to an Insteon plug-in, the humidifier is plugged into.
For both systems I use both high and a low humidity user settings. On a cyclic bases, synchronised with my central air handler fan, I trigger a program that runs the system for a very short cycle or a long cycle, depending on current home humidity (from the ecobee). The fan synchronisation is so that systems requiring the fan do not run the fan for only one purpose, keeping the total run time down and thus economy of the system.
The systems shut down when they detect I am on vacation, not needed, or wrong season.