Thanks for all the help and advice guys! Using your help, and the internet here is the setup I am purchasing.
From Smart Home
ISY-99i/IR PRO INSTEON Compatible Automation Controller with Dual-Band PLM and IR Control $420.28
Venstar Thermostat - INSTEON Remote Control Thermostat 7-Day Programmable $200.00
SwitchLinc Relay - INSTEON Remote Control On/Off Switch (Non-Dimming), White $45.99 (i'll start out with 15 and see what happens)
Access Point - INSTEON Wireless Phase Coupler $39.99 (probably need 6)
I'd like to have two touch screens, so I am going to pickup either two used android tablets, or two used ipad 1 tablets and wall mount them. (its way cheaper than any of the insteon in wall touch screens i've found. I think this covers everything to get started and have a good base for my future home automation equipment. In the home automation world this stuff seems to be close to top notch.
Please throw your two cents in if you see something I am missing, otherwise I'll post back after everything is installed!