My only problem with that board is expansion, it only has 2 PCIe x1 and 1 PCI slot. For HTPC use you want the more the merrier when it comes to that area.
ICH10R southbridge is a nice feature.
It would probably be very nice for client box but a server IMHO needs more expansion.
Not to be obtuse, but why would you need more? In my setup, the media server and htpc are two different beasts. I was using a normal ATX setup with separate video card, which worked fine but now that you can get HDMI and decent on board sound, what else is needed that this flavor of motherboard can't do?
I currently have an Asus motherboard with the G45 chipset. I use it for general computing. I used it to rip my DVD's to the hard drive, and as a proof of concept for the media center pc, and when I play ripped DVD's, it will play fine for a while, then the video will start stuttering and the screen starts blacking out, then the whole thing hangs and has to be powered off and back on to use it again. I know certain video types do not trigger this problem (don't recall off hand which ones), but for what I want to do with it the G45 chipset is a no go as it stands now. For general use and playing a couple games, it works great. It's just when I try to play videos the thing goes haywire.
Sorry to hear you're having that kind of trouble, Matt. Don't know what to say other than the Asus I linked to has been rock solid for me when playing ripped DVDs via ZP. I haven't had to do anything with it in nearly a month (including reboot it) since I set it up and I usually watch a few movies a week with it.