I have my house as Area 1 and the Attached garage as Area 2. I use a Keyfob button to simultaneously disarm the garage area and open the garage door. This way, even if I loose the Keyfob, someone finding it can only gain access to the garage. They would still have to disarm the rest of the house by using the keypad located just inside the door leading from the garage into the rest of the house.
I have a friend who uses a separate Area for a large gun safe he has in his basement so he can have different users (He and wife, not the kids) than for the House Area (in case the kids found out the safe combination).