How much money you got?
At the very least, I would do 2, maybe 3. For a point of reference, assume the breakfast nook is North.
I would put one in the Northeast corner of the Family room - that should catch anyone coming through a FR window, coming in from the garage/laundry, or coming up from the basement.
I would put another one in the Southwest corner of the Foyer to catch anyone coming down the foyer hall, up/down the stairs, in the front door, or out of the Dining or Living rooms.
As a third, I would consider doing one in the Northeast corner of the Breakfast Nook. If you want to spend a little more, the Northwest corner of the Hall to the garage, and maybe the Northwest of the Garage (but not if you will open garage when armed). These locations will also be useful for automation purposes.
I would do one in the upstairs hall only if it is reasonable that someone can get in or out through a second story window or door.
In my mind, motions serve three purposes - 1) as a backup for door and window contacts, not a substitute; 2) a way to catch somebody who might be hiding in the house and waiting until you leave; and 3) for automation and occupancy purposes.
Mark