If you want to spend a fortune, go with Lutron HomeWorks 8 series, hardwired, if open to studs. HomeWorks 4 Series is slightly less expensive and less 'invasive' (high voltage loads not home run). New HomeWorks hardwired systems being released late winter/early spring. Difficult to DIY, but not impossible (search for Herdfan's posts).
Put your hands on the switches and keypads, before deciding, to get a feel for quality and finish. I think Lutron Maestro switches are all the same (automated and nonautomated) - you can just look at them at Home Depot/Lowes.
If someone else is doing the wiring, then talk to a few installers.
I agree, hardwired switches/keypads probably better than powerline or RF, but not necessarily. I'm not familiar with all of the hardwired systems. ALC seems to be the most popular DIY hardwired solution, here at cocoontech.
And welcome.