Just looking at the diagram from the DBH cut sheet, here's what I see happens when the RJ45 wires are reversed:
12VDC+ sourced from the DBH will be on the wht/grn rather than the brown. That will inject 12V onto the white for the keypad harness and also the wht/orng on the cat 5/6 as they are all connected together. That, in turn, injects +12 onto databus B on the keypad, and also fires +12 back to databus A on the DBH.
12VDC- from the DBH will be on the cat 5/6 green which is connected to orange on the cat 5/6 and green of the keypad. That feeds 12VDC- to the keypad's databus A and the DBH's databus B.
So I think what's happened at the keypad is that you've got a 12 VDC differential across databus A and databus B. If I recall my RS485 correctly, the protocol works on differential voltage, with 0 volts being "off state" and 1.5 VDC being "on state". The actual voltage to ground for A and B can float (within limits) but the differential needs to be within limits. So by injecting a 12V differential, you pushed about 10x the normal state voltage into the databus connections at the keypad.
It MAY have fed back to the DBH, hard to tell, but hopefully there's some isolation at the DBH module so any damage might be limited to a single port. Hard to tell without getting the details of the circuit board design.