Philip, All you really need is x2 going from the breaker panel to the switch-box. The black would be HOT and the white would be NEUTRAL. That is also all you need for an Insteon or UPB transmitter.
If the switch controls a light fixture, you would use an x2 there as well. The black wire would then be SWITCHED-HOT and the white wire would be NEUTRAL return.
If you wanted the light fixture to support a ceiling fan as well, you could use an x3 wire, making the black wire HOT, and the red wire SWITCHED-HOT.
If you also wanted the ceiling fan to be switched from the switch-box, you could use the x3 and make both black and red switched, or you could run two X2 cables.